Table 3 Summary of genome-wide mutations in mismatch defective cells
Mismatch TypeMutationNumbera% Total
Single-base indelbDeletions at homopolymers201181.2
Insertions at homopolymers1616.5
Subtotal217587.7
Single base substitutionTransitions1124.5
Transversions461.9
Subtotal1586.4
Larger indelaInsertions at microsatellites863.5
Deletions at microsatellites602.4
Subtotal1465.9
  • a Data from all strains defined and msh2 null.

  • b Indel, insertion/deletion, only two indels were not at homopolymers or larger microsatellites.