Table 6 Global burden of rare CNVs in European ASD cases vs. PDx controls
TypeMeasureMean
ASDMean
ControlsMean ratio ASD/controlsP-value
AllNo. CNV2.6809422.5658481.050.0575976
AllTotal CNV size, kb124.50112.921.100.1804119
AllTotal no. genes3.8501072.5602681.500.2345081
Deletions onlyNo. CNV1.9582251.7737931.100.0046012a
Deletions onlyTotal CNV size, kb54.2948.811.110.1043462
Deletions onlyTotal number of genes1.7415140.98344831.770.0087554a
Duplications onlyNo. CNV1.5493831.6012660.970.7716051
Duplications onlyTotal CNV size, kb101.6696.021.110.3778319
Duplications onlyTotal no. genes3.4907412.4952531.400.8564186
  • a Significant differences (P ≤ 0.01) are indicated.