Gene to GO MF test for over-representation
GOMFID Pvalue OddsRatio ExpCount Count Size Term
GO:0005515 0.000 2.138 22 40 1102 protein binding
GO:0004716 0.000 Inf 0 2 2 receptor signaling protein tyrosine kinase activity
GO:0008142 0.000 Inf 0 2 2 oxysterol binding
GO:0008170 0.000 5.684 1 7 70 N-methyltransferase activity
GO:0015631 0.001 5.342 1 7 74 tubulin binding
GO:0042054 0.001 5.990 1 6 57 histone methyltransferase activity
GO:0003725 0.001 10.626 0 4 23 double-stranded RNA binding
GO:0008092 0.001 2.958 5 13 242 cytoskeletal protein binding
GO:0004022 0.001 99.913 0 2 3 alcohol dehydrogenase (NAD) activity
GO:0045294 0.001 99.913 0 2 3 alpha-catenin binding
GO:0000989 0.001 3.217 4 11 188 transcription factor binding transcription factor activity
GO:0008017 0.001 5.355 1 6 63 microtubule binding
GO:0003713 0.002 4.019 2 8 110 transcription coactivator activity
GO:0032934 0.002 9.173 1 4 26 sterol binding
GO:0000988 0.002 3.074 4 11 196 protein binding transcription factor activity
GO:0003714 0.002 6.177 1 5 46 transcription corepressor activity
GO:0030506 0.002 49.950 0 2 4 ankyrin binding
GO:0018024 0.003 5.754 1 5 49 histone-lysine N-methyltransferase activity
GO:0008276 0.003 4.691 1 6 71 protein methyltransferase activity
GO:0003712 0.003 3.046 4 10 179 transcription cofactor activity
GO:0016278 0.003 5.625 1 5 50 lysine N-methyltransferase activity
GO:0016279 0.003 5.625 1 5 50 protein-lysine N-methyltransferase activity
GO:0045296 0.004 11.583 0 3 16 cadherin binding
GO:0008757 0.004 3.715 2 7 103 S-adenosylmethionine-dependent methyltransferase activity
GO:0005496 0.005 6.299 1 4 36 steroid binding
GO:0050839 0.007 4.514 1 5 61 cell adhesion molecule binding
GO:0004525 0.008 19.973 0 2 7 ribonuclease III activity
GO:0042800 0.008 8.360 0 3 21 histone methyltransferase activity (H3-K4 specific)
GO:0003682 0.008 2.590 4 10 208 chromatin binding
GO:0001871 0.009 3.207 2 7 118 pattern binding
GO:0030247 0.009 3.207 2 7 118 polysaccharide binding
GO:0003779 0.011 3.094 2 7 122 actin binding
GO:0005319 0.012 4.911 1 4 45 lipid transporter activity
GO:0016614 0.014 2.525 4 9 191 oxidoreductase activity, acting on CH-OH group of donors
GO:0004725 0.015 3.712 1 5 73 protein tyrosine phosphatase activity
GO:0005488 0.016 1.572 123 135 6201 binding
GO:0043566 0.016 3.605 1 5 75 structure-specific DNA binding
GO:0016811 0.017 4.374 1 4 50 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides
GO:0050662 0.019 2.377 4 9 202 coenzyme binding
GO:0019534 0.019 11.090 0 2 11 toxin transporter activity
GO:0030246 0.020 2.365 4 9 203 carbohydrate binding
GO:0008168 0.020 2.511 3 8 170 methyltransferase activity
GO:0047800 0.020 Inf 0 1 1 cysteamine dioxygenase activity
GO:0000009 0.020 Inf 0 1 1 alpha-1,6-mannosyltransferase activity
GO:0008808 0.020 Inf 0 1 1 cardiolipin synthase activity
GO:0005325 0.020 Inf 0 1 1 peroxisomal fatty-acyl-CoA transporter activity
GO:0031210 0.020 Inf 0 1 1 phosphatidylcholine binding
GO:0004034 0.020 Inf 0 1 1 aldose 1-epimerase activity
GO:0071936 0.020 Inf 0 1 1 coreceptor activity involved in Wnt receptor signaling pathway
GO:0015246 0.020 Inf 0 1 1 fatty-acyl group transporter activity
GO:0004408 0.020 Inf 0 1 1 holocytochrome-c synthase activity
GO:0051903 0.020 Inf 0 1 1 S-(hydroxymethyl)glutathione dehydrogenase activity
GO:0042586 0.020 Inf 0 1 1 peptide deformylase activity
GO:0004122 0.020 Inf 0 1 1 cystathionine beta-synthase activity
GO:0003839 0.020 Inf 0 1 1 gamma-glutamylcyclotransferase activity
GO:0052917 0.020 Inf 0 1 1 dol-P-Man:Man(7)GlcNAc(2)-PP-Dol alpha-1,6-mannosyltransferase activity
GO:0004757 0.020 Inf 0 1 1 sepiapterin reductase activity
GO:0030572 0.020 Inf 0 1 1 phosphatidyltransferase activity
GO:0030523 0.020 Inf 0 1 1 dihydrolipoamide S-acyltransferase activity
GO:0004742 0.020 Inf 0 1 1 dihydrolipoyllysine-residue acetyltransferase activity
GO:0080007 0.020 Inf 0 1 1 S-nitrosoglutathione reductase activity
GO:0015607 0.020 Inf 0 1 1 fatty-acyl-CoA transporter activity
GO:0050072 0.020 Inf 0 1 1 m7G(5')pppN diphosphatase activity
GO:0004552 0.020 Inf 0 1 1 octanol dehydrogenase activity
GO:0042903 0.020 Inf 0 1 1 tubulin deacetylase activity
GO:0047860 0.020 Inf 0 1 1 diiodophenylpyruvate reductase activity
GO:0016810 0.020 3.408 2 5 79 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
GO:0008201 0.021 4.105 1 4 53 heparin binding
GO:0016741 0.022 2.449 3 8 174 transferase activity, transferring one-carbon groups
GO:0005520 0.023 9.980 0 2 12 insulin-like growth factor binding
GO:0008270 0.024 1.537 23 32 1135 zinc ion binding
GO:0045182 0.031 8.315 0 2 14 translation regulator activity
GO:0050661 0.037 4.417 1 3 37 NADP binding
GO:0015026 0.039 49.648 0 1 2 coreceptor activity
GO:0031405 0.039 49.648 0 1 2 lipoic acid binding
GO:0070410 0.039 49.648 0 1 2 co-SMAD binding
GO:0005324 0.039 49.648 0 1 2 long-chain fatty acid transporter activity
GO:0004097 0.039 49.648 0 1 2 catechol oxidase activity
GO:0004044 0.039 49.648 0 1 2 amidophosphoribosyltransferase activity
GO:0005219 0.039 49.648 0 1 2 ryanodine-sensitive calcium-release channel activity
GO:0000213 0.039 49.648 0 1 2 tRNA-intron endonuclease activity
GO:0030275 0.039 49.648 0 1 2 LRR domain binding
GO:0015245 0.039 49.648 0 1 2 fatty acid transporter activity
GO:0003726 0.039 49.648 0 1 2 double-stranded RNA adenosine deaminase activity
GO:0003858 0.039 49.648 0 1 2 3-hydroxybutyrate dehydrogenase activity
GO:0036263 0.039 49.648 0 1 2 L-DOPA monooxygenase activity
GO:0036264 0.039 49.648 0 1 2 dopamine monooxygenase activity
GO:0046790 0.039 49.648 0 1 2 virion binding
GO:0004711 0.039 49.648 0 1 2 ribosomal protein S6 kinase activity
GO:0016716 0.039 49.648 0 1 2 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen
GO:0017174 0.039 49.648 0 1 2 glycine N-methyltransferase activity
GO:0004530 0.039 49.648 0 1 2 deoxyribonuclease I activity
GO:0004503 0.039 49.648 0 1 2 monophenol monooxygenase activity
GO:0005009 0.039 49.648 0 1 2 insulin-activated receptor activity
GO:0016657 0.039 49.648 0 1 2 oxidoreductase activity, acting on NADH or NADPH, nitrogenous group as acceptor
GO:0004672 0.040 1.808 8 13 381 protein kinase activity
GO:0005539 0.040 3.292 1 4 65 glycosaminoglycan binding
GO:0008289 0.041 1.846 7 12 344 lipid binding
GO:0016616 0.041 2.299 3 7 161 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0003690 0.042 4.171 1 3 39 double-stranded DNA binding
GO:0015485 0.044 6.649 0 2 17 cholesterol binding
GO:0048037 0.047 1.919 5 10 275 cofactor binding
GO:0043169 0.047 1.327 57 68 2887 cation binding
GO:0043167 0.048 1.326 57 68 2888 ion binding
GO:0046914 0.048 1.399 29 38 1474 transition metal ion binding
GO:0004713 0.052 2.593 2 5 102 protein tyrosine kinase activity
GO:0008138 0.054 5.866 0 2 19 protein tyrosine/serine/threonine phosphatase activity
GO:0004521 0.055 2.951 1 4 72 endoribonuclease activity
GO:0008061 0.056 3.660 1 3 44 chitin binding
GO:0008134 0.057 2.908 1 4 73 transcription factor binding
GO:0001129 0.058 24.821 0 1 3 TBP-class protein binding RNA polymerase II transcription factor activity involved in preinitiation complex assembly
GO:0001132 0.058 24.821 0 1 3 TBP-class protein binding RNA polymerase II transcription factor activity
GO:0001102 0.058 24.821 0 1 3 RNA polymerase II activating transcription factor binding
GO:0070412 0.058 24.821 0 1 3 R-SMAD binding
GO:0005159 0.058 24.821 0 1 3 insulin-like growth factor receptor binding
GO:0070883 0.058 24.821 0 1 3 pre-miRNA binding
GO:0017017 0.058 24.821 0 1 3 MAP kinase tyrosine/serine/threonine phosphatase activity
GO:0004420 0.058 24.821 0 1 3 hydroxymethylglutaryl-CoA reductase (NADPH) activity
GO:0016443 0.058 24.821 0 1 3 bidentate ribonuclease III activity
GO:0016174 0.058 24.821 0 1 3 NAD(P)H oxidase activity
GO:0001083 0.058 24.821 0 1 3 RNA polymerase II basal transcription factor binding transcription factor activity
GO:0004772 0.058 24.821 0 1 3 sterol O-acyltransferase activity
GO:0043560 0.058 24.821 0 1 3 insulin receptor substrate binding
GO:0043548 0.058 24.821 0 1 3 phosphatidylinositol 3-kinase binding
GO:0034736 0.058 24.821 0 1 3 cholesterol O-acyltransferase activity
GO:0005010 0.058 24.821 0 1 3 insulin-like growth factor-activated receptor activity
GO:0042043 0.058 24.821 0 1 3 neurexin family protein binding
GO:0019838 0.059 5.539 0 2 20 growth factor binding
GO:0042802 0.064 2.066 4 7 178 identical protein binding
GO:0003729 0.064 2.785 2 4 76 mRNA binding
GO:0004344 0.064 5.247 0 2 21 glucose dehydrogenase activity
GO:0016651 0.066 3.409 1 3 47 oxidoreductase activity, acting on NADH or NADPH
GO:0046872 0.067 1.293 55 65 2792 metal ion binding
GO:0019198 0.070 4.984 0 2 22 transmembrane receptor protein phosphatase activity
GO:0004715 0.070 4.984 0 2 22 non-membrane spanning protein tyrosine kinase activity
GO:0005001 0.070 4.984 0 2 22 transmembrane receptor protein tyrosine phosphatase activity
GO:0008812 0.076 4.746 0 2 23 choline dehydrogenase activity
GO:0004721 0.076 2.304 2 5 114 phosphoprotein phosphatase activity
GO:0003956 0.077 16.545 0 1 4 NAD(P)+-protein-arginine ADP-ribosyltransferase activity
GO:0047522 0.077 16.545 0 1 4 15-oxoprostaglandin 13-oxidase activity
GO:0050327 0.077 16.545 0 1 4 testosterone 17-beta-dehydrogenase (NAD+) activity
GO:0043014 0.077 16.545 0 1 4 alpha-tubulin binding
GO:0004067 0.077 16.545 0 1 4 asparaginase activity
GO:0032440 0.077 16.545 0 1 4 2-alkenal reductase [NAD(P)] activity
GO:0005178 0.077 16.545 0 1 4 integrin binding
GO:0047035 0.077 16.545 0 1 4 testosterone dehydrogenase (NAD+) activity
GO:0035174 0.077 16.545 0 1 4 histone serine kinase activity
GO:0004303 0.077 16.545 0 1 4 estradiol 17-beta-dehydrogenase activity
GO:0048027 0.077 16.545 0 1 4 mRNA 5'-UTR binding
GO:0036132 0.077 16.545 0 1 4 13-prostaglandin reductase activity
GO:0034185 0.077 16.545 0 1 4 apolipoprotein binding
GO:0043559 0.077 16.545 0 1 4 insulin binding
GO:0017169 0.077 16.545 0 1 4 CDP-alcohol phosphatidyltransferase activity
GO:0033549 0.077 16.545 0 1 4 MAP kinase phosphatase activity
GO:0019789 0.077 16.545 0 1 4 SUMO ligase activity
GO:0033613 0.077 16.545 0 1 4 activating transcription factor binding
GO:0008294 0.077 16.545 0 1 4 calcium- and calmodulin-responsive adenylate cyclase activity
GO:0005047 0.077 16.545 0 1 4 signal recognition particle binding
GO:0008026 0.088 2.201 2 5 119 ATP-dependent helicase activity
GO:0070035 0.088 2.201 2 5 119 purine NTP-dependent helicase activity
GO:0031491 0.095 12.407 0 1 5 nucleosome binding
GO:0047617 0.095 12.407 0 1 5 acyl-CoA hydrolase activity
GO:0000340 0.095 12.407 0 1 5 RNA 7-methylguanosine cap binding
GO:0070290 0.095 12.407 0 1 5 NAPE-specific phospholipase D activity
GO:0000403 0.095 12.407 0 1 5 Y-form DNA binding
GO:0051635 0.095 12.407 0 1 5 bacterial cell surface binding
GO:0050750 0.095 12.407 0 1 5 low-density lipoprotein particle receptor binding
GO:0050840 0.095 12.407 0 1 5 extracellular matrix binding
GO:0035242 0.095 12.407 0 1 5 protein-arginine omega-N asymmetric methyltransferase activity
GO:0043176 0.095 12.407 0 1 5 amine binding
GO:0050664 0.095 12.407 0 1 5 oxidoreductase activity, acting on NADH or NADPH, oxygen as acceptor
GO:0016727 0.095 12.407 0 1 5 oxidoreductase activity, acting on CH or CH2 groups, oxygen as acceptor
GO:0004855 0.095 12.407 0 1 5 xanthine oxidase activity
GO:0048487 0.095 12.407 0 1 5 beta-tubulin binding
GO:0016594 0.095 12.407 0 1 5 glycine binding
GO:0004579 0.095 12.407 0 1 5 dolichyl-diphosphooligosaccharide-protein glycotransferase activity
GO:0005041 0.095 12.407 0 1 5 low-density lipoprotein receptor activity
GO:0004630 0.095 12.407 0 1 5 phospholipase D activity
GO:0016682 0.095 12.407 0 1 5 oxidoreductase activity, acting on diphenols and related substances as donors, oxygen as acceptor
GO:0016891 0.104 2.774 1 3 57 endoribonuclease activity, producing 5'-phosphomonoesters
GO:0005102 0.111 2.038 3 5 128 receptor binding
GO:0016763 0.112 3.689 1 2 29 transferase activity, transferring pentosyl groups
GO:0030060 0.113 9.925 0 1 6 L-malate dehydrogenase activity
GO:0001105 0.113 9.925 0 1 6 RNA polymerase II transcription coactivator activity
GO:0000400 0.113 9.925 0 1 6 four-way junction DNA binding
GO:0005218 0.113 9.925 0 1 6 intracellular ligand-gated calcium channel activity
GO:0035241 0.113 9.925 0 1 6 protein-arginine omega-N monomethyltransferase activity
GO:0001085 0.113 9.925 0 1 6 RNA polymerase II transcription factor binding
GO:0008469 0.113 9.925 0 1 6 histone-arginine N-methyltransferase activity
GO:0034237 0.113 9.925 0 1 6 protein kinase A regulatory subunit binding
GO:0050997 0.113 9.925 0 1 6 quaternary ammonium group binding
GO:0016857 0.113 9.925 0 1 6 racemase and epimerase activity, acting on carbohydrates and derivatives
GO:0016888 0.113 9.925 0 1 6 endodeoxyribonuclease activity, producing 5'-phosphomonoesters
GO:0004576 0.113 9.925 0 1 6 oligosaccharyl transferase activity
GO:0042803 0.115 1.871 3 6 167 protein homodimerization activity
GO:0016893 0.121 2.582 1 3 61 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
GO:0019901 0.126 3.433 1 2 31 protein kinase binding
GO:0004568 0.126 3.433 1 2 31 chitinase activity
GO:0005543 0.126 1.657 5 8 251 phospholipid binding
GO:0070325 0.131 8.270 0 1 7 lipoprotein particle receptor binding
GO:0046969 0.131 8.270 0 1 7 NAD-dependent histone deacetylase activity (H3-K9 specific)
GO:0046970 0.131 8.270 0 1 7 NAD-dependent histone deacetylase activity (H4-K16 specific)
GO:0046975 0.131 8.270 0 1 7 histone methyltransferase activity (H3-K36 specific)
GO:0000339 0.131 8.270 0 1 7 RNA cap binding
GO:0004000 0.131 8.270 0 1 7 adenosine deaminase activity
GO:0032129 0.131 8.270 0 1 7 histone deacetylase activity (H3-K9 specific)
GO:0034041 0.131 8.270 0 1 7 sterol-transporting ATPase activity
GO:0042799 0.131 8.270 0 1 7 histone methyltransferase activity (H4-K20 specific)
GO:0042813 0.131 8.270 0 1 7 Wnt-activated receptor activity
GO:0005542 0.131 8.270 0 1 7 folic acid binding
GO:0016289 0.131 8.270 0 1 7 CoA hydrolase activity
GO:0008312 0.131 8.270 0 1 7 7S RNA binding
GO:0008453 0.131 8.270 0 1 7 alanine-glyoxylate transaminase activity
GO:0031078 0.131 8.270 0 1 7 histone deacetylase activity (H3-K14 specific)
GO:0016726 0.131 8.270 0 1 7 oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor
GO:0043546 0.131 8.270 0 1 7 molybdopterin cofactor binding
GO:0004854 0.131 8.270 0 1 7 xanthine dehydrogenase activity
GO:0016892 0.131 8.270 0 1 7 endoribonuclease activity, producing 3'-phosphomonoesters
GO:0034739 0.131 8.270 0 1 7 histone deacetylase activity (H4-K16 specific)
GO:0032041 0.131 8.270 0 1 7 NAD-dependent histone deacetylase activity (H3-K14 specific)
GO:0003697 0.132 3.318 1 2 32 single-stranded DNA binding
GO:0016702 0.132 3.318 1 2 32 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen
GO:0016740 0.138 1.263 28 34 1423 transferase activity
GO:0003727 0.139 3.211 1 2 33 single-stranded RNA binding
GO:0004540 0.141 2.061 2 4 101 ribonuclease activity
GO:0051213 0.146 3.110 1 2 34 dioxygenase activity
GO:0001190 0.148 7.087 0 1 8 RNA polymerase II transcription factor binding transcription factor activity involved in positive regulation of transcription
GO:0034979 0.148 7.087 0 1 8 NAD-dependent protein deacetylase activity
GO:0035173 0.148 7.087 0 1 8 histone kinase activity
GO:0015278 0.148 7.087 0 1 8 calcium-release channel activity
GO:0004470 0.148 7.087 0 1 8 malic enzyme activity
GO:0004407 0.148 7.087 0 1 8 histone deacetylase activity
GO:0016418 0.148 7.087 0 1 8 S-acetyltransferase activity
GO:0005544 0.148 7.087 0 1 8 calcium-dependent phospholipid binding
GO:0033764 0.148 7.087 0 1 8 steroid dehydrogenase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017136 0.148 7.087 0 1 8 NAD-dependent histone deacetylase activity
GO:0016791 0.154 1.708 4 6 182 phosphatase activity
GO:0004519 0.154 1.708 4 6 182 endonuclease activity
GO:0016773 0.156 1.409 10 13 479 phosphotransferase activity, alcohol group as acceptor
GO:0005509 0.158 1.452 8 11 393 calcium ion binding
GO:0004842 0.159 1.689 4 6 184 ubiquitin-protein ligase activity
GO:0003723 0.164 1.306 16 20 798 RNA binding
GO:0016679 0.165 6.201 0 1 9 oxidoreductase activity, acting on diphenols and related substances as donors
GO:0034040 0.165 6.201 0 1 9 lipid-transporting ATPase activity
GO:0005217 0.165 6.201 0 1 9 intracellular ligand-gated ion channel activity
GO:0000217 0.165 6.201 0 1 9 DNA secondary structure binding
GO:0031625 0.165 6.201 0 1 9 ubiquitin protein ligase binding
GO:0044389 0.165 6.201 0 1 9 small conjugating protein ligase binding
GO:0050681 0.165 6.201 0 1 9 androgen receptor binding
GO:0016229 0.165 6.201 0 1 9 steroid dehydrogenase activity
GO:0033558 0.165 6.201 0 1 9 protein deacetylase activity
GO:0016854 0.165 6.201 0 1 9 racemase and epimerase activity
GO:0017105 0.165 6.201 0 1 9 acyl-CoA delta11-desaturase activity
GO:0038024 0.167 2.843 1 2 37 cargo receptor activity
GO:0043021 0.174 2.763 1 2 38 ribonucleoprotein complex binding
GO:0019900 0.174 2.763 1 2 38 kinase binding
GO:0019787 0.180 1.623 4 6 191 small conjugating protein ligase activity
GO:0004029 0.182 5.511 0 1 10 aldehyde dehydrogenase (NAD) activity
GO:0030371 0.182 5.511 0 1 10 translation repressor activity
GO:0003756 0.182 5.511 0 1 10 protein disulfide isomerase activity
GO:0034437 0.182 5.511 0 1 10 glycoprotein transporter activity
GO:0016273 0.182 5.511 0 1 10 arginine N-methyltransferase activity
GO:0016274 0.182 5.511 0 1 10 protein-arginine N-methyltransferase activity
GO:0008301 0.182 5.511 0 1 10 DNA binding, bending
GO:0016780 0.182 5.511 0 1 10 phosphotransferase activity, for other substituted phosphate groups
GO:0016894 0.182 5.511 0 1 10 endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters
GO:0016862 0.182 5.511 0 1 10 intramolecular oxidoreductase activity, interconverting keto- and enol-groups
GO:0016864 0.182 5.511 0 1 10 intramolecular oxidoreductase activity, transposing S-S bonds
GO:0016846 0.182 5.511 0 1 10 carbon-sulfur lyase activity
GO:0004549 0.182 5.511 0 1 10 tRNA-specific ribonuclease activity
GO:0004500 0.182 5.511 0 1 10 dopamine beta-monooxygenase activity
GO:0004674 0.186 1.492 6 8 277 protein serine/threonine kinase activity
GO:0042578 0.186 1.538 5 7 235 phosphoric ester hydrolase activity
GO:0003676 0.192 1.181 43 48 2149 nucleic acid binding
GO:0005057 0.195 2.550 1 2 41 receptor signaling protein activity
GO:0008235 0.195 2.550 1 2 41 metalloexopeptidase activity
GO:0016301 0.197 1.339 10 13 502 kinase activity
GO:0043498 0.198 4.959 0 1 11 cell surface binding
GO:0019210 0.198 4.959 0 1 11 kinase inhibitor activity
GO:0016715 0.198 4.959 0 1 11 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen
GO:0017127 0.198 4.959 0 1 11 cholesterol transporter activity
GO:0004563 0.198 4.959 0 1 11 beta-N-acetylhexosaminidase activity
GO:0000030 0.198 4.959 0 1 11 mannosyltransferase activity
GO:0005200 0.203 2.486 1 2 42 structural constituent of cytoskeleton
GO:0005484 0.214 4.508 0 1 12 SNAP receptor activity
GO:0046332 0.214 4.508 0 1 12 SMAD binding
GO:0015248 0.214 4.508 0 1 12 sterol transporter activity
GO:0051010 0.214 4.508 0 1 12 microtubule plus-end binding
GO:0051018 0.214 4.508 0 1 12 protein kinase A binding
GO:0005546 0.214 4.508 0 1 12 phosphatidylinositol-4,5-bisphosphate binding
GO:0051540 0.228 1.867 2 3 83 metal cluster binding
GO:0051536 0.228 1.867 2 3 83 iron-sulfur cluster binding
GO:0046983 0.229 1.491 4 6 207 protein dimerization activity
GO:0008553 0.230 4.132 0 1 13 hydrogen-exporting ATPase activity, phosphorylative mechanism
GO:0046961 0.230 4.132 0 1 13 proton-transporting ATPase activity, rotational mechanism
GO:0004016 0.230 4.132 0 1 13 adenylate cyclase activity
GO:0043178 0.230 4.132 0 1 13 alcohol binding
GO:0004181 0.230 4.132 0 1 13 metallocarboxypeptidase activity
GO:0005545 0.230 4.132 0 1 13 1-phosphatidylinositol binding
GO:0016755 0.230 4.132 0 1 13 transferase activity, transferring amino-acyl groups
GO:0019213 0.230 4.132 0 1 13 deacetylase activity
GO:0016725 0.230 4.132 0 1 13 oxidoreductase activity, acting on CH or CH2 groups
GO:0019239 0.230 4.132 0 1 13 deaminase activity
GO:0043531 0.230 4.132 0 1 13 ADP binding
GO:0005021 0.230 4.132 0 1 13 vascular endothelial growth factor-activated receptor activity
GO:0008762 0.230 4.132 0 1 13 UDP-N-acetylmuramate dehydrogenase activity
GO:0017046 0.245 3.813 0 1 14 peptide hormone binding
GO:0035258 0.245 3.813 0 1 14 steroid hormone receptor binding
GO:0016417 0.245 3.813 0 1 14 S-acyltransferase activity
GO:0017112 0.245 3.813 0 1 14 Rab guanyl-nucleotide exchange factor activity
GO:0004520 0.245 3.813 0 1 14 endodeoxyribonuclease activity
GO:0016881 0.246 1.454 4 6 212 acid-amino acid ligase activity
GO:0005085 0.258 1.581 3 4 130 guanyl-nucleotide exchange factor activity
GO:0015459 0.260 3.541 0 1 15 potassium channel regulator activity
GO:0016215 0.260 3.541 0 1 15 acyl-CoA desaturase activity
GO:0004768 0.260 3.541 0 1 15 stearoyl-CoA 9-desaturase activity
GO:0004745 0.260 3.541 0 1 15 retinol dehydrogenase activity
GO:0000062 0.260 3.541 0 1 15 fatty-acyl-CoA binding
GO:0030695 0.265 1.371 5 7 262 GTPase regulator activity
GO:0035091 0.270 1.695 2 3 91 phosphatidylinositol binding
GO:0016491 0.274 1.191 16 19 821 oxidoreductase activity
GO:0060589 0.274 1.354 5 7 265 nucleoside-triphosphatase regulator activity
GO:0051537 0.275 3.304 0 1 16 2 iron, 2 sulfur cluster binding
GO:0045735 0.275 3.304 0 1 16 nutrient reservoir activity
GO:0001076 0.276 1.986 1 2 52 RNA polymerase II transcription factor binding transcription factor activity
GO:0004714 0.284 1.947 1 2 53 transmembrane receptor protein tyrosine kinase activity
GO:0016615 0.289 3.097 0 1 17 malate dehydrogenase activity
GO:0030374 0.289 3.097 0 1 17 ligand-dependent nuclear receptor transcription coactivator activity
GO:0030228 0.289 3.097 0 1 17 lipoprotein particle receptor activity
GO:0004712 0.289 3.097 0 1 17 protein serine/threonine/tyrosine kinase activity
GO:0016717 0.289 3.097 0 1 17 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water
GO:0016814 0.289 3.097 0 1 17 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines
GO:0003993 0.289 3.097 0 1 17 acid phosphatase activity
GO:0016788 0.298 1.181 15 17 739 hydrolase activity, acting on ester bonds
GO:0050136 0.303 2.915 0 1 18 NADH dehydrogenase (quinone) activity
GO:0003730 0.303 2.915 0 1 18 mRNA 3'-UTR binding
GO:0008137 0.303 2.915 0 1 18 NADH dehydrogenase (ubiquinone) activity
GO:0004623 0.303 2.915 0 1 18 phospholipase A2 activity
GO:0004620 0.306 1.838 1 2 56 phospholipase activity
GO:0050660 0.314 1.552 2 3 99 flavin adenine dinucleotide binding
GO:0003954 0.317 2.752 0 1 19 NADH dehydrogenase activity
GO:0042562 0.317 2.752 0 1 19 hormone binding
GO:0004536 0.317 2.752 0 1 19 deoxyribonuclease activity
GO:0019199 0.328 1.741 1 2 59 transmembrane receptor protein kinase activity
GO:0015929 0.331 2.607 0 1 20 hexosaminidase activity
GO:0004004 0.331 2.607 0 1 20 ATP-dependent RNA helicase activity
GO:0019829 0.331 2.607 0 1 20 cation-transporting ATPase activity
GO:0008565 0.335 1.710 1 2 60 protein transporter activity
GO:0051539 0.335 1.710 1 2 60 4 iron, 4 sulfur cluster binding
GO:0004386 0.342 1.315 4 5 194 helicase activity
GO:0004177 0.343 1.681 1 2 61 aminopeptidase activity
GO:0016701 0.343 1.681 1 2 61 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen
GO:0016628 0.344 2.477 0 1 21 oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor
GO:0005548 0.344 2.477 0 1 21 phospholipid transporter activity
GO:0008186 0.344 2.477 0 1 21 RNA-dependent ATPase activity
GO:0005086 0.344 2.477 0 1 21 ARF guanyl-nucleotide exchange factor activity
GO:0005044 0.344 2.477 0 1 21 scavenger receptor activity
GO:0016655 0.344 2.477 0 1 21 oxidoreductase activity, acting on NADH or NADPH, quinone or similar compound as acceptor
GO:0019902 0.357 2.358 0 1 22 phosphatase binding
GO:0035257 0.357 2.358 0 1 22 nuclear hormone receptor binding
GO:0051427 0.357 2.358 0 1 22 hormone receptor binding
GO:0032947 0.357 2.358 0 1 22 protein complex scaffold
GO:0003677 0.368 1.095 25 27 1262 DNA binding
GO:0004033 0.370 2.251 0 1 23 aldo-keto reductase (NADP) activity
GO:0004003 0.370 2.251 0 1 23 ATP-dependent DNA helicase activity
GO:0016860 0.370 2.251 0 1 23 intramolecular oxidoreductase activity
GO:0019899 0.371 1.315 3 4 155 enzyme binding
GO:0004601 0.383 2.153 0 1 24 peroxidase activity
GO:0015035 0.383 2.153 0 1 24 protein disulfide oxidoreductase activity
GO:0043022 0.383 2.153 0 1 24 ribosome binding
GO:0016706 0.383 2.153 0 1 24 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0000049 0.383 2.153 0 1 24 tRNA binding
GO:0016684 0.383 2.153 0 1 24 oxidoreductase activity, acting on peroxide as acceptor
GO:0016790 0.386 1.525 1 2 67 thiolester hydrolase activity
GO:0016879 0.388 1.206 5 6 253 ligase activity, forming carbon-nitrogen bonds
GO:0031406 0.393 1.502 1 2 68 carboxylic acid binding
GO:0008238 0.401 1.328 2 3 115 exopeptidase activity
GO:0016757 0.407 1.248 3 4 163 transferase activity, transferring glycosyl groups
GO:0016772 0.420 1.081 16 17 799 transferase activity, transferring phosphorus-containing groups
GO:0009975 0.430 1.833 1 1 28 cyclase activity
GO:0016769 0.430 1.833 1 1 28 transferase activity, transferring nitrogenous groups
GO:0008483 0.430 1.833 1 1 28 transaminase activity
GO:0016849 0.430 1.833 1 1 28 phosphorus-oxygen lyase activity
GO:0042623 0.433 1.118 7 8 363 ATPase activity, coupled
GO:0005088 0.434 1.375 1 2 74 Ras guanyl-nucleotide exchange factor activity
GO:0008374 0.442 1.767 1 1 29 O-acyltransferase activity
GO:0016247 0.442 1.767 1 1 29 channel regulator activity
GO:0005198 0.446 1.105 7 8 367 structural molecule activity
GO:0016298 0.448 1.338 2 2 76 lipase activity
GO:0004518 0.449 1.126 5 6 270 nuclease activity
GO:0004843 0.453 1.706 1 1 30 ubiquitin-specific protease activity
GO:0004553 0.460 1.158 3 4 175 hydrolase activity, hydrolyzing O-glycosyl compounds
GO:0015036 0.464 1.649 1 1 31 disulfide oxidoreductase activity
GO:0043130 0.464 1.649 1 1 31 ubiquitin binding
GO:0003724 0.464 1.649 1 1 31 RNA helicase activity
GO:0043565 0.470 1.100 5 6 276 sequence-specific DNA binding
GO:0003824 0.474 1.024 93 94 4686 catalytic activity
GO:0051015 0.474 1.596 1 1 32 actin filament binding
GO:0019783 0.474 1.596 1 1 32 small conjugating protein-specific protease activity
GO:0005083 0.478 1.131 4 4 179 small GTPase regulator activity
GO:0044212 0.495 1.141 3 3 133 transcription regulatory region DNA binding
GO:0001077 0.495 1.499 1 1 34 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0005097 0.495 1.499 1 1 34 Rab GTPase activator activity
GO:0004523 0.495 1.499 1 1 34 ribonuclease H activity
GO:0001067 0.500 1.133 3 3 134 regulatory region nucleic acid binding
GO:0000975 0.500 1.133 3 3 134 regulatory region DNA binding
GO:0001228 0.505 1.454 1 1 35 RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003678 0.505 1.454 1 1 35 DNA helicase activity
GO:0008237 0.512 1.081 4 4 187 metallopeptidase activity
GO:0004872 0.522 1.025 9 9 443 receptor activity
GO:0005254 0.525 1.373 1 1 37 chloride channel activity
GO:0003705 0.525 1.373 1 1 37 RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0016836 0.525 1.373 1 1 37 hydro-lyase activity
GO:0004180 0.534 1.336 1 1 38 carboxypeptidase activity
GO:0003899 0.534 1.336 1 1 38 DNA-directed RNA polymerase activity
GO:0005506 0.535 1.025 6 6 295 iron ion binding
GO:0004888 0.535 1.025 6 6 295 transmembrane signaling receptor activity
GO:0016874 0.538 1.013 8 8 398 ligase activity
GO:0016798 0.541 1.040 4 4 194 hydrolase activity, acting on glycosyl bonds
GO:0005253 0.544 1.301 1 1 39 anion channel activity
GO:0004871 0.544 1.005 9 9 451 signal transducer activity
GO:0060089 0.544 1.005 9 9 451 molecular transducer activity
GO:0036094 0.547 0.993 44 44 2227 small molecule binding
GO:0032182 0.553 1.267 1 1 40 small conjugating protein binding
GO:0016597 0.553 1.267 1 1 40 amino acid binding
GO:0016209 0.562 1.235 1 1 41 antioxidant activity
GO:0016829 0.567 1.021 3 3 148 lyase activity
GO:0016705 0.572 0.991 5 5 254 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0015108 0.579 1.176 1 1 43 chloride transmembrane transporter activity
GO:0001104 0.587 1.149 1 1 44 RNA polymerase II transcription cofactor activity
GO:0042302 0.587 1.149 1 1 44 structural constituent of cuticle
GO:0000166 0.590 0.973 42 41 2106 nucleotide binding
GO:0097159 0.590 0.973 42 41 2106 organic cyclic compound binding
GO:1901265 0.590 0.973 42 41 2106 nucleoside phosphate binding
GO:0042393 0.596 1.122 1 1 45 histone binding
GO:0005244 0.600 0.997 2 2 101 voltage-gated ion channel activity
GO:0022832 0.600 0.997 2 2 101 voltage-gated channel activity
GO:0005524 0.605 0.963 29 28 1454 ATP binding
GO:0019904 0.612 1.073 1 1 47 protein domain specific binding
GO:0004221 0.612 1.073 1 1 47 ubiquitin thiolesterase activity
GO:0080030 0.612 1.073 1 1 47 methyl indole-3-acetate esterase activity
GO:0080031 0.612 1.073 1 1 47 methyl salicylate esterase activity
GO:0080032 0.612 1.073 1 1 47 methyl jasmonate esterase activity
GO:0004190 0.621 0.958 2 2 105 aspartic-type endopeptidase activity
GO:0070001 0.621 0.958 2 2 105 aspartic-type peptidase activity
GO:0016835 0.627 1.028 1 1 49 carbon-oxygen lyase activity
GO:0032559 0.628 0.950 29 28 1469 adenyl ribonucleotide binding
GO:0030554 0.628 0.950 29 28 1469 adenyl nucleotide binding
GO:0019842 0.632 0.939 2 2 107 vitamin binding
GO:0015662 0.634 1.007 1 1 50 ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
GO:0016853 0.637 0.930 2 2 108 isomerase activity
GO:0038023 0.637 0.919 6 6 327 signaling receptor activity
GO:0022836 0.637 0.918 3 3 164 gated channel activity
GO:0016627 0.642 0.987 1 1 51 oxidoreductase activity, acting on the CH-CH group of donors
GO:0051287 0.642 0.987 1 1 51 NAD binding
GO:0015078 0.642 0.987 1 1 51 hydrogen ion transmembrane transporter activity
GO:0034062 0.642 0.987 1 1 51 RNA polymerase activity
GO:0016746 0.645 0.907 3 3 166 transferase activity, transferring acyl groups
GO:0030674 0.649 0.967 1 1 52 protein binding, bridging
GO:0043492 0.649 0.901 3 3 167 ATPase activity, coupled to movement of substances
GO:0042626 0.649 0.901 3 3 167 ATPase activity, coupled to transmembrane movement of substances
GO:0008081 0.656 0.949 1 1 53 phosphoric diester hydrolase activity
GO:0005089 0.656 0.949 1 1 53 Rho guanyl-nucleotide exchange factor activity
GO:0016667 0.656 0.949 1 1 53 oxidoreductase activity, acting on a sulfur group of donors
GO:0003743 0.663 0.931 1 1 54 translation initiation factor activity
GO:0015399 0.665 0.879 3 3 171 primary active transmembrane transporter activity
GO:0015405 0.665 0.879 3 3 171 P-P-bond-hydrolysis-driven transmembrane transporter activity
GO:0016820 0.665 0.879 3 3 171 hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances
GO:0016620 0.669 0.913 1 1 55 oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
GO:0019207 0.669 0.913 1 1 55 kinase regulator activity
GO:0005099 0.669 0.913 1 1 55 Ras GTPase activator activity
GO:0070279 0.676 0.897 1 1 56 vitamin B6 binding
GO:0030170 0.676 0.897 1 1 56 pyridoxal phosphate binding
GO:0032403 0.683 0.881 1 1 57 protein complex binding
GO:0005262 0.683 0.881 1 1 57 calcium channel activity
GO:0016765 0.683 0.881 1 1 57 transferase activity, transferring alkyl or aryl (other than methyl) groups
GO:0060090 0.683 0.881 1 1 57 binding, bridging
GO:0000981 0.684 0.849 2 2 118 sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0042277 0.689 0.865 1 1 58 peptide binding
GO:0008236 0.695 0.838 4 3 179 serine-type peptidase activity
GO:0005267 0.701 0.835 1 1 60 potassium channel activity
GO:0042625 0.701 0.835 1 1 60 ATPase activity, coupled to transmembrane movement of ions
GO:0017171 0.702 0.829 4 3 181 serine hydrolase activity
GO:0016407 0.707 0.821 1 1 61 acetyltransferase activity
GO:0000982 0.707 0.821 1 1 61 RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity
GO:0004091 0.724 0.782 1 1 64 carboxylesterase activity
GO:0050253 0.724 0.782 1 1 64 retinyl-palmitate esterase activity
GO:0016758 0.727 0.781 3 2 128 transferase activity, transferring hexosyl groups
GO:0015103 0.730 0.770 1 1 65 inorganic anion transmembrane transporter activity
GO:0005096 0.731 0.774 3 2 129 GTPase activator activity
GO:0016887 0.735 0.837 9 8 475 ATPase activity
GO:0003887 0.735 0.758 1 1 66 DNA-directed DNA polymerase activity
GO:0016747 0.739 0.762 3 2 131 transferase activity, transferring acyl groups other than amino-acyl groups
GO:0030234 0.743 0.830 10 8 479 enzyme regulator activity
GO:0008094 0.746 0.735 1 1 68 DNA-dependent ATPase activity
GO:0070011 0.750 0.836 12 10 593 peptidase activity, acting on L-amino acid peptides
GO:0015085 0.756 0.713 1 1 70 calcium ion transmembrane transporter activity
GO:0052689 0.757 0.733 3 2 136 carboxylic ester hydrolase activity
GO:0016903 0.761 0.703 1 1 71 oxidoreductase activity, acting on the aldehyde or oxo group of donors
GO:0005261 0.771 0.712 3 2 140 cation channel activity
GO:0008233 0.782 0.809 12 10 611 peptidase activity
GO:0008509 0.784 0.656 2 1 76 anion transmembrane transporter activity
GO:0000976 0.788 0.647 2 1 77 transcription regulatory region sequence-specific DNA binding
GO:0015276 0.792 0.639 2 1 78 ligand-gated ion channel activity
GO:0022834 0.792 0.639 2 1 78 ligand-gated channel activity
GO:0015079 0.805 0.615 2 1 81 potassium ion transmembrane transporter activity
GO:0072509 0.809 0.607 2 1 82 divalent inorganic cation transmembrane transporter activity
GO:0003964 0.809 0.654 3 2 152 RNA-directed DNA polymerase activity
GO:0008135 0.812 0.599 2 1 83 translation factor activity, nucleic acid binding
GO:0004252 0.834 0.616 3 2 161 serine-type endopeptidase activity
GO:0004222 0.837 0.552 2 1 90 metalloendopeptidase activity
GO:0009055 0.841 0.646 5 3 230 electron carrier activity
GO:0016787 0.843 0.845 45 40 2276 hydrolase activity
GO:0005216 0.845 0.640 5 3 232 ion channel activity
GO:0004497 0.845 0.640 5 3 232 monooxygenase activity
GO:0022838 0.845 0.640 5 3 232 substrate-specific channel activity
GO:0020037 0.853 0.629 5 3 236 heme binding
GO:0015267 0.853 0.629 5 3 236 channel activity
GO:0022803 0.853 0.629 5 3 236 passive transmembrane transporter activity
GO:0035639 0.853 0.820 33 28 1652 purine ribonucleoside triphosphate binding
GO:0004175 0.854 0.697 8 6 424 endopeptidase activity
GO:0008047 0.861 0.575 3 2 172 enzyme activator activity
GO:0046906 0.861 0.618 5 3 240 tetrapyrrole binding
GO:0008234 0.867 0.495 2 1 100 cysteine-type peptidase activity
GO:0017076 0.868 0.809 33 28 1669 purine nucleotide binding
GO:0032553 0.868 0.809 33 28 1669 ribonucleotide binding
GO:0032555 0.868 0.809 33 28 1669 purine ribonucleotide binding
GO:0015077 0.869 0.562 3 2 176 monovalent inorganic cation transmembrane transporter activity
GO:0022890 0.879 0.592 5 3 250 inorganic cation transmembrane transporter activity
GO:0022892 0.885 0.702 12 9 627 substrate-specific transporter activity
GO:0034061 0.890 0.528 4 2 187 DNA polymerase activity
GO:0003735 0.898 0.437 2 1 113 structural constituent of ribosome
GO:0000287 0.908 0.418 2 1 118 magnesium ion binding
GO:0004857 0.913 0.408 2 1 121 enzyme inhibitor activity
GO:0003700 0.915 0.598 8 5 409 sequence-specific DNA binding transcription factor activity
GO:0001071 0.915 0.598 8 5 409 nucleic acid binding transcription factor activity
GO:0016779 0.917 0.532 6 3 277 nucleotidyltransferase activity
GO:0046873 0.918 0.480 4 2 205 metal ion transmembrane transporter activity
GO:0004930 0.925 0.385 3 1 128 G-protein coupled receptor activity
GO:0003924 0.928 0.379 3 1 130 GTPase activity
GO:0008324 0.949 0.473 6 3 310 cation transmembrane transporter activity
GO:0022804 0.959 0.453 6 3 323 active transmembrane transporter activity
GO:0016462 0.965 0.597 16 10 804 pyrophosphatase activity
GO:0016818 0.965 0.596 16 10 805 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
GO:0016817 0.967 0.592 16 10 810 hydrolase activity, acting on acid anhydrides
GO:0005215 0.971 0.594 18 11 885 transporter activity
GO:0015075 0.977 0.442 9 4 437 ion transmembrane transporter activity
GO:0017111 0.978 0.548 16 9 784 nucleoside-triphosphatase activity
GO:0005525 0.989 0.220 4 1 221 GTP binding
GO:0019001 0.991 0.207 5 1 234 guanyl nucleotide binding
GO:0032561 0.991 0.207 5 1 234 guanyl ribonucleotide binding
GO:0022891 0.996 0.350 11 4 543 substrate-specific transmembrane transporter activity
GO:0022857 0.996 0.405 14 6 699 transmembrane transporter activity