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Ancestry Informative Marker Set for Han Chinese Population

Hui-Qi Qu, Quan Li, Shuhua Xu, Joseph B. McCormick, Susan P. Fisher-Hoch, Momiao Xiong, Ji Qian and Li Jin
G3: Genes, Genomes, Genetics March 1, 2012 vol. 2 no. 3 339-341; https://doi.org/10.1534/g3.112.001941
Hui-Qi Qu
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
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  • For correspondence: huiqi.qu@uth.tmc.edulijin.fudan@gmail.com
Quan Li
Endocrine Genetics Lab, McGill University Health Center (Montreal Children’s Hospital), Montréal, Québec H3H 1P3, Canada
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Shuhua Xu
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of China
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Joseph B. McCormick
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
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Susan P. Fisher-Hoch
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
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Momiao Xiong
School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas 77030
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Ji Qian
State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of China
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Li Jin
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of ChinaState Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of ChinaChina Medical City (CMC) Institute of Health Sciences, Taizhou, Jiangsu 225300, People’s Republic of China
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Abstract

The population of Han Chinese is ∼1.226 billion people. Genetic heterogeneity between northern Han Chinese (N-Han) and southern Han Chinese (S-Han) has been demonstrated by recent genome-wide studies. As an initial step toward health disparities and personalized medicine in Chinese population, this study developed a set of ancestry informative markers (AIM) for Han Chinese population.

  • ancestry informative marker
  • Han Chinese
  • genetic association study
  • population structure
  • Received November 16, 2011.
  • Accepted January 8, 2012.
  • Copyright © 2012 Qu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution Unported License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Volume 2 Issue 3, March 2012

G3: Genes|Genomes|Genetics: 2 (3)

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Ancestry Informative Marker Set for Han Chinese Population

Hui-Qi Qu, Quan Li, Shuhua Xu, Joseph B. McCormick, Susan P. Fisher-Hoch, Momiao Xiong, Ji Qian and Li Jin
G3: Genes, Genomes, Genetics March 1, 2012 vol. 2 no. 3 339-341; https://doi.org/10.1534/g3.112.001941
Hui-Qi Qu
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: huiqi.qu@uth.tmc.edulijin.fudan@gmail.com
Quan Li
Endocrine Genetics Lab, McGill University Health Center (Montreal Children’s Hospital), Montréal, Québec H3H 1P3, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shuhua Xu
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of China
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Joseph B. McCormick
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
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Susan P. Fisher-Hoch
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
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Momiao Xiong
School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas 77030
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Ji Qian
State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of China
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Li Jin
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of ChinaState Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of ChinaChina Medical City (CMC) Institute of Health Sciences, Taizhou, Jiangsu 225300, People’s Republic of China
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  • For correspondence: huiqi.qu@uth.tmc.edulijin.fudan@gmail.com
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Citation

Ancestry Informative Marker Set for Han Chinese Population

Hui-Qi Qu, Quan Li, Shuhua Xu, Joseph B. McCormick, Susan P. Fisher-Hoch, Momiao Xiong, Ji Qian and Li Jin
G3: Genes, Genomes, Genetics March 1, 2012 vol. 2 no. 3 339-341; https://doi.org/10.1534/g3.112.001941
Hui-Qi Qu
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: huiqi.qu@uth.tmc.edulijin.fudan@gmail.com
Quan Li
Endocrine Genetics Lab, McGill University Health Center (Montreal Children’s Hospital), Montréal, Québec H3H 1P3, Canada
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Shuhua Xu
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Joseph B. McCormick
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
  • Find this author on Google Scholar
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  • Search for this author on this site
Susan P. Fisher-Hoch
School of Public Health, University of Texas Health Science Center at Houston, Brownsville, Texas 78520
  • Find this author on Google Scholar
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  • Search for this author on this site
Momiao Xiong
School of Public Health, University of Texas Health Science Center at Houston, Houston, Texas 77030
  • Find this author on Google Scholar
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  • Search for this author on this site
Ji Qian
State Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Li Jin
Chinese Academy of Sciences and Max Planck Society (CAS-MPG) Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, People’s Republic of ChinaState Key Laboratory of Genetic Engineering and Ministry of Education (MOE) Key Laboratory of Contemporary Anthropology, School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200433, People’s Republic of ChinaChina Medical City (CMC) Institute of Health Sciences, Taizhou, Jiangsu 225300, People’s Republic of China
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • For correspondence: huiqi.qu@uth.tmc.edulijin.fudan@gmail.com

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